At Hometech Therapies, we offer a full spectrum of specialized therapies, including but not limited to IVIG, Factor VIII, and Factor VII & IX Antihemophilics.

Intravenous Immune Globulin (IVIG or IGIV) is a sterile solution of concentrated antibodies extracted from healthy donors which is administered into a vein. IVIG infusion therapy is used to treat disorders of the immune system, such as ITP (Immune Thrombocytopenic Purpura) and PID (Primary Immune Deficiency disorders) or to boost immune response to serious illness, and to treat immunosuppressed recipients of bone marrow transplants.

Anti-hemophilic factor is a sterile solution of concentrated Factor VII, VIII, or IX, protein substances in the blood plasma that are essential to the blood clotting process. Factor VIII is administered intravenously for the treatment of Factor VIII deficiency, also known as Hemophilia A. Factor IX is administered intravenously for the treatment of Factor IX deficiency, also known as Hemophilia B.

IVIG Comparison Table

IVIG Product Manufacturer Viral Inactivation Sodium Content (5% concentration) Sugar Content Carimune® NF CSL Behring pH 4.0 Trace pepsin Nanofiltration 0% water 0.9% saline 5% sucrose Gamunex® 10% (replace Gamimune® N S/D 10%) Talecris pH 4.25 Low salt Caprylate Trace No sugar; glycine based Gammagard® S/D Baxter Healthcare Corp. Solvent / detergent 0.85% 2% glucose Gammar® P.I.V. ZLB Behring Pasteurization 0.5% 5% sucrose Iveegam® EN Baxter Healthcare Corp. PEG Trypsin 3 mg/ml 5% glucose Octagam® 5% Octapharma Cohn-Oncley pH 4.0 Solvent / detergent < 30 mmol/L 10% maltose

Download a table of additional characteristics of available immune globulin products.

Antihemophilic Factor VIII Comparison Table

Factor Product & Manufacturer Viral Removal Viral Inactivation Plasma Source Storage Diluent Volume Helixate® FS ZLB Behring Monoclonal Antibody Immuno-Affinity Chromotography Solvent / Detergent Recombinant Refrigeration 2.5ml Kogenate® FS Bayer N/A Solvent / Detergent Treatment Recombinant Refrigeration however, it may be stored up to three months at room temperature not exceeding 25° C (77° F) 250iu:2.5ml 500iu:2.5ml 1000iu:2.5ml Recombinate Baxter Immuno-Affinity Chromotography and Ion Exchange Chromotography N/A N/A; a recombinant FVIII Refrigeration 2°-8°C (36°-46°F) or room temperature, not to exceed 30°C (86°F) 10ml Advate Baxter Immuno-Affinity Chromotography and Ion Exchange Chromotography Solvent / Detergent N/A; a Plasma / Albumin - Free Method recombinant FVIII 2°-8°C (36°-46°F). May be stored at room temperature, 22°-28°C (72°-82°F) for up to 6 months or until expiration date, whichever comes first. 5ml Humate-P® ZLB Behring Absorption and Precipitation Process Pasteurization Paid Donor Pool Refrigeration or 6 months at room temperature 10ml, 20ml or 30ml Monarc-M American Red Cross Blood Services Monoclonal Antibody Immuno-Affinity Chromotography Solvent / Detergent Volunteer Donor Pool Refrigeration 2°-8°C (36°-46°F) or room temperature, not to exceed 30°C (86°F) 10ml Hemofil M Baxter Monoclonal Antibody Immuno-Affinity Chromotography Solvent / Detergent Paid Donor Pool Refrigeration 2°-8°C (36°-46°F) or room temperature, not to exceed 30°C (86°F) 10ml Monoclate-P® ZLB Behring Monoclonal Antibody Immuno-Affinity Chromotography Pasteurization Paid Donor Pool Refrigeration or room temperature for 6 months 10ml or 20ml Koate®-DVI Talecris N/A Solvent / Detergent Heat Treatment 80°C x 72 hours U.S. donors Refrigeration (2°-8°C); room temperature (up to 25°C) for 6 months 250iu:5ml 500iu:5ml 1000iu:10ml Alphanate® Grifols Affinity Chromotography heparin-coupled, cross linked agarose which has an affinity to the heparin binding domain of vWF/F VIII: C Complex, 3.5% PEG Precipitation Solvent / Detergent treatment with a mixture of Tri (nbutyl) phosphate (TNBP) and Polysorbate 80 / Dry Heat Cycle at 80° for 72 hrs. / Lyophilization Paid Donor Pool Refrigeration 2°-8°C (36°-46°F) Do not freeze diluent, or room temperature not to exceed 30°C for 2 months 500iu:5ml 1000iu & 1500iu:10ml

Antihemophilic Factor VII & IX Comparison Table

Factor Product & Manufacturer Viral Removal Viral Inactivation Plasma Source Storage Diluent Volume AlphaNine SD Grifols DEAE Chromotography/ Dual Affinity Chromotography/ Nanofiltration Solvent/DetergentTreatment with a mixture of Tri (n-butyl) phosphate (TNBP) and Polysorbate 80 Paid Donor Pool 2°-8°C Do not freeze diluent or room temperature not to exceed 30°C for up to 1 month 10ml Bebulin VH Baxter N/A Vapor heat treatment 60°C 10 hours, 190 mbar; then 80° C 1 hour, 375 mbar Paid Donor Pool Refrigeration 2°-8°C 20ml NovoSeven® Novo Nordisk Chromatographic Purification Process to remove exogenous viruses N/A N/A Refrigeration 2°-8°C (36°-46°F) Do not freeze diluent, or room temperature not to exceed 30°C for 2 months 1.2mg vial + 2.2ml 2.4mg vial + 4.3ml 4.8mg vial + 8.5ml Sterile water for injection, USP Feiba VH Baxter N/A Vapor Heat Treatment 60°C 10hrs, 190mbar., then 80°C 1 hour, 370mbar. Paid Donor Pool Refrigeration 2°-8°C (36°-46°F) May be stored at room temperature not to exceed 25°C (77°F) for up to 6 months or until expiration date, whichever comes first. 20ml Mononine® ZLB Behring Monoclonal Antibody Immunoaffinity Chromotography and Ultrafiltration Sodium Thiocyanate Paid Donor Pool Refrigeration or room temperature for one month 5ml or 10ml Profilnine® SD Grifols DEAE Chromotography Solvent / Detergent Treatment with a mixture of Tri (n-butyl) phosphate (TNBP) and Polysorbate 80 Paid Donor Pool Refrigeration (2°-8°C); Do not freeze diluent or room temperature not to exceed 30°C for up to 3 months 500iu : 5ml 1000 & 1500iu : 10ml